| Saavedra (28,864) | Sabin (18,498) | Sabo (26,196) |
| Sacco (16,068) | Sachs (24,084) | Sack (11,766) |
| Sackett (22,484) | Sacks (15,910) | Saddler (16,788) |
| Sadler (76,241) | Sadowski (13,667) | Saenz (62,332) |
| Safford (15,933) | Sage (45,548) | Sager (39,256) |
| Sain (10,603) | Saint (40,306) | Salas (114,826) |
| Salazar (295,292) | Salcedo (27,582) | Salcido (16,832) |
| Saldana (53,615) | Saldivar (23,774) | Sale (12,474) |
| Saleh (10,483) | Salem (11,151) | Salerno (21,420) |
| Sales (14,142) | Salgado (75,125) | Salinas (150,414) |
| Salisbury (47,683) | Sallee (16,480) | Salley (12,898) |
| Sally (10,052) | Salmon (45,935) | Salomon (11,930) |
| Salsbury (10,211) | Salter (48,091) | Saltzman (11,085) |
| Salvador (22,773) | Salvatore (14,047) | Salyer (17,973) |
| Salyers (14,066) | Sam (25,102) | Samaniego (10,916) |
| Sammons (24,554) | Sample (45,224) | Samples (25,689) |
| Sampson (148,343) | Sams (47,682) | Samson (33,789) |
| Samuel (59,252) | Samuels (69,734) | Samuelson (28,795) |
| San (22,371) | Sanabria (13,809) | Sanborn (54,812) |
| Sanches (18,806) | Sanchez (1,295,878) | Sand (15,237) |
| Sandberg (26,703) | Sander (37,814) | Sanders (884,961) |
| Sanderson (121,794) | Sandford (15,060) | Sandifer (13,138) |
| Sandler (12,454) | Sandlin (21,827) | Sandoval (244,312) |
| Sandra (11,271) | Sands (73,444) | Sandy (26,331) |
| Sanford (154,631) | Sang (13,288) | Sanger (15,444) |
| Sansone (10,325) | Santa (21,662) | Santamaria (16,869) |
| Santana (112,583) | Santiago (291,711) | Santillan (17,633) |
| Santo (13,138) | Santoro (18,730) | Santos (315,932) |
| Santoyo (10,614) | Sapp (69,660) | Sarabia (10,886) |
| Sargeant (9,870) | Sargent (116,600) | Sarmiento (18,582) |
| Sartin (9,978) | Sarver (19,032) | Sass (16,742) |
| Sasser (18,419) | Sato (10,383) | Satterfield (44,947) |
| Satterwhite (13,343) | Sattler (12,502) | Sauceda (16,623) |
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